全文获取类型
收费全文 | 23787篇 |
免费 | 1016篇 |
国内免费 | 266篇 |
专业分类
耳鼻咽喉 | 12篇 |
儿科学 | 660篇 |
妇产科学 | 175篇 |
基础医学 | 2041篇 |
口腔科学 | 57篇 |
临床医学 | 4674篇 |
内科学 | 6795篇 |
皮肤病学 | 54篇 |
神经病学 | 475篇 |
特种医学 | 993篇 |
外国民族医学 | 1篇 |
外科学 | 3064篇 |
综合类 | 2663篇 |
现状与发展 | 2篇 |
预防医学 | 612篇 |
眼科学 | 12篇 |
药学 | 1681篇 |
8篇 | |
中国医学 | 386篇 |
肿瘤学 | 704篇 |
出版年
2023年 | 320篇 |
2022年 | 540篇 |
2021年 | 851篇 |
2020年 | 747篇 |
2019年 | 887篇 |
2018年 | 900篇 |
2017年 | 688篇 |
2016年 | 620篇 |
2015年 | 832篇 |
2014年 | 1767篇 |
2013年 | 1682篇 |
2012年 | 1208篇 |
2011年 | 1369篇 |
2010年 | 1146篇 |
2009年 | 1191篇 |
2008年 | 1226篇 |
2007年 | 1113篇 |
2006年 | 1035篇 |
2005年 | 795篇 |
2004年 | 679篇 |
2003年 | 554篇 |
2002年 | 472篇 |
2001年 | 360篇 |
2000年 | 336篇 |
1999年 | 311篇 |
1998年 | 217篇 |
1997年 | 242篇 |
1996年 | 235篇 |
1995年 | 221篇 |
1994年 | 211篇 |
1993年 | 172篇 |
1992年 | 149篇 |
1991年 | 146篇 |
1990年 | 117篇 |
1989年 | 102篇 |
1988年 | 135篇 |
1987年 | 106篇 |
1986年 | 82篇 |
1985年 | 139篇 |
1984年 | 177篇 |
1983年 | 103篇 |
1982年 | 110篇 |
1981年 | 100篇 |
1980年 | 105篇 |
1979年 | 84篇 |
1978年 | 63篇 |
1977年 | 75篇 |
1976年 | 79篇 |
1975年 | 72篇 |
1973年 | 57篇 |
排序方式: 共有10000条查询结果,搜索用时 778 毫秒
1.
2.
Andreas Lundin Martin Annborn Ola Borgquist Joachim Düring Johan Undén Christian Rylander 《Acta anaesthesiologica Scandinavica》2023,67(5):655-662
Patients admitted to intensive care after cardiac arrest are at risk of circulatory shock and early mortality due to cardiovascular failure. The aim of this study was to evaluate the ability of the veno-arterial pCO2 difference (∆pCO2; central venous CO2 – arterial CO2) and lactate to predict early mortality in postcardiac arrest patients. This was a pre-planned prospective observational sub-study of the target temperature management 2 trial. The sub-study patients were included at five Swedish sites. Repeated measurements of ∆pCO2 and lactate were conducted at 4, 8, 12, 16, 24, 48, and 72 h after randomization. We assessed the association between each marker and 96-h mortality and their prognostic value for 96-h mortality. One hundred sixty-three patients were included in the analysis. Mortality at 96 h was 17%. During the initial 24 h, there was no difference in ∆pCO2 levels between 96-h survivors and non-survivors. ∆pCO2 measured at 4 h was associated with an increased risk of death within 96 h (adjusted odds ratio: 1.15; 95% confidence interval [CI]: 1.02–1.29; p = .018). Lactate levels were associated with poor outcome over multiple measurements. The area under the receiving operating curve to predict death within 96 h was 0.59 (95% CI: 0.48–0.74) and 0.82 (95% CI: 0.72–0.92) for ∆pCO2 and lactate, respectively. Our results do not support the use of ∆pCO2 to identify patients with early mortality in the postresuscitation phase. In contrast, non-survivors demonstrated higher lactate levels in the initial phase and lactate identified patients with early mortality with moderate accuracy. 相似文献
3.
4.
A male in his 90 s consulted a doctor because he experienced several days of general fatigue and dyspnea. He was diagnosed with heart failure, and diuretic medications taken for 3 days relieved his symptoms. However, he was found dead on the morning of the fourth day after consultation. He had received a third dose of coronavirus disease 2019 (COVID-19) vaccine approximately 2 weeks before death. An autopsy revealed dissection of the ascending aorta and pericardial hemotamponade. The heart showed a white villous surface, and the pericardium was fibrously thick. Microscopic examination revealed pericarditis with predominantly macrophage and lymphocyte infiltration. These histological findings were compatible with those of post-vaccination myocarditis. To the best of our knowledge, histopathologically proven pericarditis after COVID-19 vaccination has not been reported. In the present case, extended inflammation of the aortic adventitia was a possible cause of aortic wall fragility followed by dissection. 相似文献
5.
K.V.P. SaiKiran Debasish Biswal Sonu Kumari Agrawal Priyam Batra Tanu Sagar S.K. Choudhary Nishant Verma Rama Chaudhry 《Indian journal of medical microbiology》2022,40(2):274-278
PurposeAnaerobic infections are common yet life-threatening. They are being recovered from all sites of the body, including the cardiovascular system. This study was aimed to determine the retrospective analysis on the isolation of anaerobes in cardiovascular samples received for a decade-long duration. It helps in knowing the frequency of isolation of anaerobic causes of cardiovascular infection.MethodsAll cardiovascular samples from the department of Cardio-thoracic vascular surgery from January 2010 to December 2020 were studied.ResultsOf 601 samples received, predominant samples were vegetations and valvular tissues of 258, followed by 98 samples of pericardial tissues, 92 samples of embolus, 90 samples of blood and post-operative collections, and 63 excised aneurysms and vascular grafts. Of the total, 15 samples grew anaerobes where Clostridium species were the predominant isolates. Clostridioides difficile was isolated in 2 samples.ConclusionsAnaerobes in cardiovascular samples are uncommon yet form a significant cause of morbidity and mortality. Most infections are from the contiguous spread, penetrating trauma, and hematogenous causing endocarditis or valvular infections. These conditions and samples form the seat of infectious focus and clinical suspicion towards the anaerobic cause of these conditions, especially in conventional routine culture-negative samples. Timely diagnosis of anaerobic infections plays a vital role in the good prognostic outcome of patients undergoing cardiothoracic and vascular surgery. 相似文献
6.
7.
8.
Sara Järpestam Louise Martinell Christian Rylander Linus Lilja 《Acta anaesthesiologica Scandinavica》2023,67(9):1249-1255
Background
European guidelines recommend targeted temperature management (TTM) in post-cardiac arrest care. A large multicentre clinical trial, however, showed no difference in mortality and neurological outcome when comparing hypothermia to normothermia with early treatment of fever. The study results were valid given a strict protocol for the assessment of prognosis using defined neurological examinations. With the current range of recommended TTM temperatures, and applicable neurological examinations, procedures may differ between hospitals and the variation of clinical practice in Sweden is not known.Aim
The aim of this study was to investigate current practice in post-resuscitation care after cardiac arrest as to temperature targets and assessment of neurological prognosis in Swedish intensive care units (ICUs).Methods
A structured survey was conducted by telephone or e-mail in all Levels 2 and 3 (= 53) Swedish ICUs during the spring of 2022 with a secondary survey in April 2023.Results
Five units were not providing post-cardiac arrest care and were excluded. The response rate was 43/48 (90%) of the eligible units. Among the responding ICUs, normothermia (36–37.7°C) was applied in all centres (2023). There was a detailed routine for the assessment of neurological prognosis in 38/43 (88%) ICUs. Neurological assessment was applied 72–96 h after return of spontaneous circulation in 32/38 (84%) units. Electroencephalogram and computed tomography and/or magnetic resonance imaging were the most common technical methods available.Conclusion
Swedish ICUs use normothermia including early treatment of fever in post-resuscitation care after cardiac arrest and almost all apply a detailed routine for the assessment of neurological prognosis. However, available methods for prognostic evaluation varies between hospitals. 相似文献9.
10.